BIOACTIVITY TESTING SERVICES

Fast, reliable and inexpensive pre-clinical claim validation for cosmeceutical
products before you start spending heavily on clinical studies.


We specialize in custom tests and method development for:


* Scientific validation of bioactivity claims

* Testing of active materials for purported bioactivity

* Quantification of active materials in final products
Sunny BioDiscovery, Inc.
Welcome!
Highlights:

Over 20 standard tests for skin-relevant bioactivities (collagen
and hyaluronic acid stimulation, antioxidant activity, inhibition of
MMPs and Advenced Glycation Endproducts…)

Tests on Cell Cultures and Skin Substitutes (penetration,
whitening, irritation…)

Antibody and DNA Microarrays (MMPs, inflammatory cytokines…)

Phototoxicity, viability, human dermal fibroblast & keratinocyte
proliferation assays

HPLC, LC-MS, Fluorometry, TLC, Spectrophotometry, skin
oxygenation



Selected test examples:



































Located in the San Francisco Bay Area and among the orchards of Santa
Paula (Ventura county, Southern CA), Sunny BioDiscovery, Inc. has been in
the Research & Development business for over 7 years and our science has
been honored by several NIH grants, including from the National Institute on
Aging and National Cancer Institute.

We have worked with many publicly and privately held companies, enabling
them to validate the bioactive potential of their ingredients. You can entrust
your materials to us for a fast, precise and professional service.

At Sunny BioDiscovery, your materials will be custom-tested under the
supervision of an experienced PhD or MD scientist, who will then prepare a
written report and will be available for discussing the results over the phone.  
We guarantee the quality and the confidentiality of our services.
Test
 Approximate
turn-around
Potential for angiogenesis modulation
(endothelial cell growth) Test # 01
2 weeks
In vitro angiogenesis modulation (tube
formation on matrigel ) Test # 02        
2-3 weeks
In vitro angiogenesis modulation
(tridimensional tube network) Test # 03
5-7 weeks
Collagen Production (human dermal
fibroblasts) Test # 04
2-4 weeks
Elastase InhibitionTest # 05
 2-4 weeks
Fibroblast ProliferationTest # 06
 2-4 weeks
Keratinocyte ProliferationTest # 07
 2-4 weeks
Matrix Metalloproteinase (MMP) Inhibition
Test # 08
 2-4 weeks
Lipolysis Test # 09
 2-4 weeks
Superoxide DesmutaseStimulation Test # 10
 2-4 weeks
UV-induced Lipid Peroxidation Test # 11
 2-4 weeks
3T3 NRU Phototoxicity Test #12
 2 weeks
Neutral Red Uptake (fibroblasts) Test # 13
 2-4 weeks
Neutral Red Uptake (keratinocytes) Test#14
 2-4 weeks
In vitro irritation on EpiDerm(TM) Test#15
 2-4 weeks
Percutaneous absorption on EpiDerm(TM)
Test #1 6
 4-6 weeks
Effect on B16  (skin) and MDA MD435
(breast) cell lines Test # 17
 2 weeks
Tyrosinase Inhibition Test # 18
 2-4 weeks
Melanocyte Pigmentation Test # 19
 2-4 weeks
Anti-glycation (AGE) Test # 20
 4 weeks
ORAC (anti-oxidant) Test # 21
 1 week