BIOACTIVITY TESTING SERVICES
Fast, reliable and inexpensive pre-clinical claim validation for cosmeceutical products before you start spending heavily on clinical studies.
We specialize in custom tests and method development for:
* Scientific validation of bioactivity claims
* Testing of active materials for new bioactivity
* Development of new cosmetic claim concepts backed by scientific publications (see "Science" page)
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Sunny BioDiscovery, Inc.
Welcome!
Highlights:
Over 20 standard tests for skin-relevant bioactivities (collagen
and hyaluronic acid stimulation, antioxidant activity, inhibition of
MMPs, inflammation and Advenced Glycation Endproducts…)
Tests on Cell Cultures and Skin Substitutes (penetration,
whitening, irritation…)
PCR arrays (Anti-aging, anti-inflammation, skin structure, wound
healing, and more)
Phototoxicity, viability, human dermal fibroblast & keratinocyte
proliferation assays
HPLC, LC-MS, Fluorometry, TLC, Spectrophotometry, skin
oxygenation
Selected test examples:
Located among the orchards of Santa Paula (Ventura county, Southern CA),
Sunny BioDiscovery, Inc. has been in the Research & Development business
for over 10 years and our science has been honored by several NIH grants,
including from the National Institute on Aging and National Cancer Institute.
We have worked with many publicly and privately held companies, enabling
them to validate the bioactive potential of their ingredients. You can entrust
your materials to us for a fast, precise and professional service.
At Sunny BioDiscovery, your materials will be custom-tested under the
supervision of an experienced PhD or MD scientist, who will then prepare a
written report and will be available for discussing the results over the phone.
We guarantee the quality and the confidentiality of our services.

Test
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Approximate turn-around
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Potential for angiogenesis modulation (endothelial cell growth) Test # 01
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2 weeks
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In vitro angiogenesis modulation (tube formation on matrigel ) Test # 02
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2-3 weeks
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In vitro angiogenesis modulation (tridimensional tube network) Test # 03
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5-7 weeks
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Collagen Production (human dermal fibroblasts) Test # 04
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2-4 weeks
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Elastase InhibitionTest # 05
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2-4 weeks
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Fibroblast ProliferationTest # 06
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2-4 weeks
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Keratinocyte ProliferationTest # 07
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2-4 weeks
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Matrix Metalloproteinase (MMP) Inhibition Test # 08
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2-4 weeks
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Lipolysis on mouse and human adipocytes Test # 09A and 09B
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2-4 weeks
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Superoxide DesmutaseStimulation Test # 10
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2-4 weeks
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UV-induced Lipid Peroxidation Test # 11
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2-4 weeks
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3T3 NRU Phototoxicity Test #12
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2 weeks
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Mitochondrial Metabolism Test # 13
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2-4 weeks
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PCR array screen of expression of any genes of interest Test # 14
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4-6 weeks
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Skin irritation on EpiDerm(TM) and ocular iritation on EpiOcular(TM) Test#15A and 15B
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2-4 weeks
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Percutaneous absorption on EpiDerm(TM) Test #1 6
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4-6 weeks
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Effect on B16 (skin) and MDA MD435 (breast) cell lines Test # 17
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2 weeks
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Tyrosinase Inhibition Test # 18
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2-4 weeks
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Melanocyte Pigmentation Test # 19
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2-4 weeks
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Anti-glycation (AGE) Test # 20
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4 weeks
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ORAC (anti-oxidant) Test # 21
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1 week
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